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胃镜检查时患者因有明显的咽部不适、屏气、呛咳、恶心、呕吐等,往往难以配合,给胃镜检查带来困难,甚至造成机械性创伤。为此,我们应用异丙酚进行镇静镇痛,效果良好,现报告如下。 一、资料和方法 1 临床资料:将胃镜检查患者（行镜下治疗者除外）共1357例,分成常规检查组（A组）和异丙酚镇静组（B组）。A组672例,男 401例,女 271例,年龄为（48.68±17.52）岁,体重（60.81±9.31）kg。B组685例,男418例,女267例,年龄为（46.97±18.40）岁,体重（61.62±7.82）kg。两组患者的男女比例、年龄结构和体重情况无差异（性别X2=0.25,年龄t=1.76,体重t=1.72,P均>0.05）。
Gastroscopy for patients with significant pharyngeal discomfort, breath, cough, nausea, vomiting, etc., often difficult to cooperate, to gastroscopy difficult, and even cause mechanical trauma. To this end, we use propofol sedation and analgesia, the effect is good, are as follows. First, the data and methods 1 clinical data: the gastroscopy patients (except for the line of treatment) were 1357 cases, divided into routine examination group (A group) and propofol sedation group (B group). A group of 672 cases, 401 males and 271 females, age (48.68 ± 17.52) years old, weight (60.81 ± 9.31) kg. There were 685 cases in group B, including 418 males and 267 females, with a mean age of (46.97 ± 18.40) years and weight of (61.62 ± 7.82) kg. The proportions of men and women, age structure and weight did not differ between the two groups (sex X2 = 0.25, age t = 1.76, body weight t = 1.72, P> 0.05).