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目的了解本地区女性生殖道支原体感染及其耐药情况。方法采用支原体鉴定药敏试剂盒对237名女性生殖道分泌物标本进行检测。结果237份标本中支原体的感染率为59.5%,不同年龄组女性生殖道支原体的感染率比较,差异具有显著性(P<0.05),其中21～40岁感染率最高(68.1%)。141份阳性标本中Uu有90例(63.8%),Mh有19例(13.5%),Uu和Mh混合感染32例(22.7%)。不同年龄组结果比较:组间差异无显著性意义(P>0.05)。耐药性试验显示:Uu对JOS和CLA的耐药性较低(3.3%和6.7%),而对CPF和ROX的耐药性较高(62.2%、60.0%);Mh对JOS和OFL的耐药性较低(0.0%、5.3%),而对ROX和AZI的耐药性较高(89.5%、84.2%);Uu+Mh混合感染对CLA和JOS的耐药性较低(15.6%和21.9%),而对CPF和ROX的耐药性较高(75.0%、68.8%)。结论女性生殖道支原体感染较高,不同年龄组中21～40岁女性支原体的感染率最高,阳性标本中以Uu感染为主。支原体的耐药试验有利于临床治疗方案的改进,选择适当的抗生素进行治疗。
Objective To understand the genital mycoplasma infection and its resistance in the area. Methods Mycoplasma identification kit was used to detect 237 specimens of female genital secretions. Results The prevalence of mycoplasma in 237 samples was 59.5%. The prevalence of mycoplasma in different age groups was significantly different (P <0.05), of which the highest infection rate was 21.1-40 years (68.1%). Among 141 positive samples, 90 (63.8%) had Uu, 19 (13.5%) had Mh, and 32 (22.7%) had mixed infection with Uu and Mh. The results of different age groups: no significant difference between groups (P> 0.05). Drug resistance test showed that Uu had lower resistance to JOS and CLA (3.3% and 6.7%), higher resistance to CPF and ROX (62.2% and 60.0%), Mh to JOS and OFL The resistance to ROX and AZI was relatively high (89.5%, 84.2%). The resistance of Uu + Mh to CLA and JOS was low (15.6% And 21.9% respectively), while CPF and ROX were more resistant (75.0%, 68.8%). Conclusions Mycoplasma infection in female genital tract is higher. The prevalence of mycoplasma in women aged 21-40 years is the highest in different age groups. Uu infection is predominant in the positive specimens. Mycoplasma resistance test is conducive to the improvement of clinical treatment options, select the appropriate antibiotics for treatment.