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例1:男,16岁,1974年自觉不规则发热一月余入院,诊断为急性粒细胞白血病,予以 COAP(CTX200mg,god,iv×lod;VCR 1 mg iv,第一天;Ara-C 50～75 mg,iv,bid.5～8 d;Pred 300 mg,qd,×5～10d)联合化疗加支持治疗,间歇8～14 d 一疗程,治疗过程中及间歇期均观察血象。在第二疗程中,患者出现头痛、项强、克氏征阳性,腰穿:颅内压高及血性脑脊液,给以鞘内注射 MTX(氨甲喋呤)10 mg+Dex(地
Example 1: Male, 16 years old, admitted to hospital in January more than one month after voluntary irregular fever, diagnosed as acute myeloid leukemia, given COAP (CTX200mg, god, iv × lod; VCR 1 mg iv, first day; Ara-C 50 ~ 75 mg, iv, bid for 5 ~ 8 d; Pred 300 mg, qd, × 5 ~ 10 d) combined with chemotherapy and supportive therapy. Intermittent 8 ~ 14 d of a course of treatment, during and during the treatment were observed blood. In the second course of treatment, patients with headache, Xiang Qiang, Klinefelter positive, lumbar puncture: high intracranial pressure and bloody cerebrospinal fluid, given intrathecal injection of MTX (methotrexate) 10 mg + Dex