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急性早幼粒细胞白血病(APL)是急性非淋巴细胞白血病的一个类型,FAB分类方案命为M_3型。因其常伴有DIC而预后不良。然而该病被诊断,用肝素和抗肿瘤药物进行适当地治疗,取得完全缓解则可延长病人的生命。微颗粒APL变异可与M_4或M_5型白血病相混淆。本文报道了三例微颗粒APL的临床和实验室所见,并强调这种不常见的形态学表现和这种变异的不良预后。三例病人发病迅猛,躯干和四肢有多处瘀
Acute promyelocytic leukemia (APL) is a type of acute non-lymphocytic leukemia and the FAB classification scheme is M_3. Because of its often accompanied by DIC and poor prognosis. However, the disease is diagnosed, properly treated with heparin and antineoplastic drugs, and complete remission can prolong the patient’s life. Microparticle APL mutations can be confused with M_4 or M_5 leukemias. This article reports on the clinical and laboratory findings of three microparticulate APLs and highlights this uncommon morphological performance and the poor prognosis of this variation. Three cases of patients with rapid onset, multiple trunk and limbs stasis