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恶性发热的后果常常是致命的,这种综合症易发生在遗传敏感的个体。典型综合症的特征为肌肉强直,严重的高热和严重的代谢紊乱。直到最近,才认识到主要是由于在全身麻醉中使用药物的刺激引起。Denborough 等认为这种综合症的症状群是复杂的。在同一而未透露家族中,用了24种麻醉药,作者把10名死者归因于这种综合症。认为氟烷和琥珀酰胆硷是激发的主要药物。但是,其它有效的吸入麻醉,如乙醚,环丙烷和安氟醚也是可疑
The consequences of malignant fever are often fatal, and the syndrome tends to occur in genetically-sensitive individuals. Typical syndromes are characterized by muscle rigidity, severe hyperthermia, and severe metabolic disorders. Until recently, it was only realized that this was mainly due to the stimulation of the use of drugs in general anesthesia. Denborough and others think the symptom cluster of this syndrome is complex. In the same but undisclosed family of 24 narcotics, the author attributed the 10 dead to the syndrome. It is believed that halothane and succinylcholine are the major drugs that are excited. However, other effective inhalational anesthesia such as diethyl ether, cyclopropane and enflurane are also suspect