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目的 :探讨离子型造影剂和非离子型造影剂的毒副反应及其合理使用。方法 :随机抽取湖北医科大学附二医院CT室 1990～ 1996年作增强CT的病例 5 6 0 0例 ,比较离子型造影剂Angiografin和非离子型造影剂Ultravist的不良反应 ,全部病例采用团注非动态CT和动态CT。结果 :卡方检验结果可知两种造影剂不良反应发病率有明显差别 ,使用离子型造影剂者不良反应的发病率显著增高。结论 :从病人的生命安全角度出发应尽量采用非离子型造影剂 ,特别是高危因素的患者。
Objective: To investigate the toxic and side effects of ionic contrast agent and nonionic contrast agent and their rational use. Methods: A total of 5600 cases of enhanced CT were randomly selected from the Second Affiliated Hospital of Hubei Medical University from 1990 to 1996. The adverse reactions of the ionic contrast agent Angiografin and the non-ionic contrast agent Ultravist were compared. Dynamic CT and dynamic CT. Results: The results of chi-square test showed that there was a significant difference in the incidence of adverse reactions between the two contrast agents. The incidence of adverse reactions was significantly higher in patients with ionic contrast agents. Conclusion: From the perspective of the patient’s life safety, non-ionic contrast agents should be used as much as possible, especially for patients at high risk.