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目的 探讨中西药结合治疗脑囊虫病的效果。方法 1.吡喹酮单剂,按20mg/kg.d×6d(每日每公斤体重20mg,分3次服用,共服6d)或10mg/kg.d×12d给药,间隔2～3个月后重复第一疗程。2.阿苯达唑单剂,按15mg/kg.d×15d给药,间隔2～3个月后重复第一疗程。3.干芜散单剂,每次1.56g,每d3次,连续服用1年。4.吡喹酮、阿苯达唑联合用药,第一疗程给予阿苯达唑20mg/kg.d×12d。后续吡喹酮30mg/kg.d×12d,间隔2～3个月后据第一疗程服药反应和囊尾蚴感染轻重给予吡喹酮30mg/kg.d×12d或50mg/kg.d×12d,2～3个月后再给予吡喹酮50mg/kg.d×12d。5.干芜散、吡喹酮、阿苯达唑联合用药,首先服用干芜散单剂6个月,后按4方法服用吡喹酮、阿苯达唑,另外间隔期间继续服用干芜散。结果 1～5种疗法的总有效率分别为69.2％,80.0％,69.6％,97.8％和94.8％,按X2检验,1.2.3种疗法的总有效率无差异(P>0.05),4.5种疗法的总有效率亦无差异(P>0.05),但4.5种疗法的总有效率明显高于1.2.3种(P<0.005),且第5疗法与第4疗法相比杀虫反应大大减轻。结论 中西药结合治疗脑囊虫病不仅能明显提高总有效率,而且可大大减轻杀虫反应的发生。
Objective To explore the effect of combining traditional Chinese and western medicine in the treatment of cerebral cysticercosis. Praziquantel single agent, according to 20mg / kg.d × 6d (daily 20mg per kilogram of body weight, taking 3 times for a total of 6d) or 10mg / kg.d × 12d administration, an interval of 2 to 3 Repeat after the first course of treatment. 2. Albendazole single dose, according to 15mg / kg.d × 15d administration, interval 2 to 3 months after the first course of treatment. 3. dry Wu scattered single agent, each 1.56g, every d3 times, taking for 1 year. Praziquantel, albendazole combination therapy, the first course of treatment given albendazole 20mg / kg.d × 12d. Subsequent praziquantel 30mg / kg.d × 12d, interval 2 ~ 3 months after the first course of treatment response and cysticerci infection severity given praziquantel 30mg / kg.d × 12d or 50mg / kg.d × 12d, Praziquantel 50mg / kg.d × 12d was given 2 to 3 months later. 5 dry Wu scattered, praziquantel, albendazole combination therapy, first taking a single dose of dry Wuwei 6 months, according to 4 methods taking praziquantel, albendazole, the other during the interval to continue taking dry Wu Shu . Results The total effective rates of 1 ~ 5 kinds of therapies were 69.2%, 80.0%, 69.6%, 97.8% and 94.8%, respectively. According to the X2 test, the total effective rate of 1.2.3 kinds of treatments was no difference (P> 0.05) The total effective rate was also no difference (P> 0.05), but the total effective rate of 4.5 kinds of therapy was significantly higher than 1.2.3 (P <0.005), and the fifth treatment significantly reduced insecticidal response compared with the fourth treatment . Conclusion Chinese and Western medicine treatment of cerebral cysticercosis can not only significantly improve the total efficiency, but also greatly reduce the occurrence of pesticidal reactions.