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目的:通过观察脑脊液分流术在64例脑肿瘤患者中的临床应用效果,探讨其临床应用的价值。方法:收集2009年1月-2010年3月我院64例脑肿瘤患者病例资料,其临床诊断均有颅内高压,对照组32例患者给予常规手术进行肿瘤切除;观察组在对照组的基础上给予脑脊液分流术,比较两组治疗效果。结果:治疗后两组颅内压均降低,观察组降低更为明显(P<0.05)。对照组完全缓解率为15.6%,部分缓解率为21.8%,病程稳定率为31.3%,病程进展率为31.3%。观察组分别为28.1%、31.3%、25%和15.6%。观察组完全缓解率和部分缓解率明显高于对照组(P<0.05.),病程进展率对照组明显高于观察组(P<0.05)。对照组术后两年内复发5例,生存超过三年的17例,生存超过五年的12例。观察组术后两年内复发的2例,生存超过三年的20例,生存超过5年的15例。和对照组比较,观察组术后病情复发率更低,生存指数更高,比较有明显差异(P<0.05)。结论:脑脊液分流术在伴颅内高压或脑积水的脑肿瘤手术中的使用效果显著,后期的手术成功率和患者生存率提高,临床上可予以更为深入的探索。
Objective: To observe the clinical application of cerebrospinal fluid shunt in 64 patients with brain tumor and explore the value of clinical application. Methods: The clinical data of 64 patients with brain tumors in our hospital from January 2009 to March 2010 were collected. The clinical data of patients with intracranial hypertension were obtained. 32 patients in the control group were given conventional surgery for tumor resection. The observation group was basal in the control group On the given cerebrospinal fluid shunt, the two groups were compared. Results: After treatment, the intracranial pressure of both groups decreased and the decrease of the observation group was more obvious (P <0.05). In the control group, the complete remission rate was 15.6%, the partial remission rate was 21.8%, the duration of disease was 31.3%, and the course of disease progression was 31.3%. The observation group were 28.1%, 31.3%, 25% and 15.6% respectively. The complete remission rate and partial remission rate of the observation group were significantly higher than those of the control group (P <0.05). The progression rate of the observation group was significantly higher than that of the observation group (P <0.05). In the control group, 5 cases relapsed within two years, 17 cases survived more than three years, and 12 cases survived for more than five years. In the observation group, 2 patients relapsed within two years after operation, 20 patients survived for more than three years and 15 patients survived for more than 5 years. Compared with the control group, the postoperative recurrence rate of the observation group was lower, and the survival index was higher, with significant difference (P <0.05). Conclusion: Cerebrospinal fluid shunt is effective in brain tumor surgery with intracranial hypertension or hydrocephalus. The success rate of surgery and the survival rate of patients are improved in the later stage. Clinically, we can explore more deeply.