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目的 比较不同用药对气管插管副反应的预防效果。方法 选择 40例剖胸肿瘤切除术全麻气管插管 ,分为A(对照组 )、B、C、D四组。麻醉诱导后B、C、D三组分别静注利多卡因 ;静注艾司洛尔 ;鼻滴硝酸甘油 ,记录插管前后MAP、SBP、HR的变化进行统计学处理。结果 C组MAP、HR、SBP组内同TO 比插管前后差异无显著性 ,组间同对照组比差异有显著性。结论 艾司洛尔可抑制心率增快和血压升高 ;利多卡因能减轻血压升高的程度 ,不抑制心率增快 ;硝酸甘油鼻滴在控制插管反应时效果不理想。
Objective To compare the preventive effects of different medications on the side effects of tracheal intubation. Methods A total of 40 cases of thoracotomy tumor resection were treated with general anesthesia and tracheal intubation. They were divided into four groups: A (control group), B, C, and D. After induction of anesthesia, B, C, and D groups were injected intravenously with lidocaine, esmolol intravenously, nasal nitroglycerin, and the changes of MAP, SBP and HR before and after intubation were statistically analyzed. Results There was no significant difference in the ratio of TO to the ratio of intubation before and after intubation in the MAP, HR, and SBP groups in the C group. There was a significant difference between the groups in comparison with the control group. Conclusion Esmolol can inhibit the increase of heart rate and blood pressure. Lidocaine can reduce the increase of blood pressure without inhibiting the increase of heart rate. The effect of nasal drops of nitroglycerin on intubation response is not satisfactory.