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探讨阴道后穹隆冲洗液β-hCG水平测定对于诊断胎膜早破(PROM)的意义。方法 采用放射免疫法测定30例胎膜早破孕妇(胎膜早破组)和60例正常孕妇(对照组,其中30例妊娠28～32周为对照组1,30例妊娠36～42周为对照组2)后穹隆冲洗液(3ml无菌生理盐水)β-hCG水平。结果 胎膜早破组后穹窿冲洗液β-hCG测定结果为324.82mlU/ml,观察组后穹窿冲洗液β-hCG测定结果为5.36mlU/ml,观察组后穹隆冲洗液β-hCG水平明显高于对照组,差异有显著性(P<0.01)。对照组1 β-hCG测定结果为6.14ml/Uml,对照组2 β-hCG测定结果为4.66mIU/ml,无显著差异(P>0.05)。结论 妊娠中晚期与妊娠晚期阴道后穹隆冲洗液β-hCG水平测定无显著差异:阴道后穹隆冲洗液β-hCG水于测定可作为胎膜早破的诊断指标之一。
To investigate the value of vaginal posterior fornix washing fluid β-hCG for the diagnosis of premature rupture of membranes (PROM) significance. Methods 30 cases of premature rupture of membranes (premature rupture of membranes) group and 60 normal pregnant women (control group, 30 cases of pregnancy 28 to 32 weeks as control group, 30 cases of 36 to 42 weeks of gestation Control group 2) After vault rinse (3ml sterile saline) β-hCG levels. Results The results of β-hCG assay were 324.82 mlU / ml, and the β-hCG value of the vault in the observation group was 5.36 mlU / ml. The β-hCG level in the vial washer fluid of the observation group was significantly higher In the control group, the difference was significant (P <0.01). The results of 1β-hCG assay in control group were 6.14ml / Uml, and the results of 2β-hCG in control group were 4.66mIU / ml with no significant difference (P> 0.05). Conclusion There is no significant difference in β-hCG level between the third trimester and the second trimester of pregnancy. Β-hCG in the posterior vaginal forging fluid can be used as a diagnostic indicator of premature rupture of membranes.