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近年来不断有合成新冠醚和冠醚衍生物的报道,关于冠醚质谱特征的研究也开始见诸文献,但这类文献的报道还不多.这可能是因为冠醚,尤其是复杂冠醚衍生物的熔点较高,在电子轰击(EI)或化学电离(CI)条件下测定存在一定困难的缘故.例如,本文讨论的双冠醚1～4都曾用EI法进行质谱测定.测定时,样品需加热到350℃,甚至400℃以上,才能得到质谱信号,而所得信号仍然相当弱.这不仅是测定本身的困难,而且可能引起离子源污染等问题.为此,我们采用快原子轰击(FAB)法测定双冠醚1～6的质谱,并对其裂解规律进行了初步的探讨.
In recent years, there are reports of synthesis of new crown ethers and crown ether derivatives, and studies on the characteristics of crown ether mass spectrometry have also begun to be seen in the literature, but not much has been reported in this literature.This may be because crown ethers, especially complex crown ethers Derivatives have relatively high melting points and some difficulties in the determination of electron impact (EI) or chemical ionization (CI) conditions, for example, the bis-crown ethers 1 to 4 discussed herein have all been subjected to mass spectrometry using the EI method , The sample should be heated to 350 ℃, even above 400 ℃ to get the mass spectrometry signal, and the resulting signal is still relatively weak.This is not only the determination of their own difficulties, but also may cause ion source pollution and other issues.To this end, we use fast atom bombardment (FAB) method for the determination of double crown ether 1 ~ 6 mass spectrometry, and the rupture of a preliminary study.