女性急性心肌梗塞的特点和近期预后因素分析

• 作 者: 李向平 王钟林 袁彬彬 赵水平
• 机 构: 湖南医科大学附属第二医院心内科，湖南省心血管病研究所
• 出 处: 临床心血管病杂志
• 发表日期: 1996年02期
• 关键词: 急性心肌梗塞 心源性休克 尿素氮水平 血清总胆固醇 心脏破裂 逐步回归分析 预后因素分析 下壁 近期预后 酶水平

对６３９例男性和２４７例女性急性心肌梗塞（ＡＭＩ）住院患者的临床和实验室检查资料进行分析。结果发现：住院期间女性ＡＭＩ患者病死率为２１．８％，男性为１３．７％，两组比较有极显著性差异（Ｐ＜０．００５）。女性组ＡＭＩ患者与男性比较，年龄较大，有高血压病史者较多，前壁梗塞较多，血清肌酸磷酸激酶水平较低，血糖水平较高，心脏破裂者较多。上述因素可能是构成女性ＡＭＩ患者预后较差的原因。此外，多因素逐步回归分析表明，心绞痛史、血尿素氮水平、血清总胆固醇水平和心源性休克是女性ＡＭＩ患者住院死亡的预测因素。

Clinical and laboratory data from 639 hospitalized men and 247 women with acute myocardial infarction (AMI) were analyzed. The results showed that the mortality rate of AMI patients during hospitalization was 21.8% and that of males was 13.7%. There was a significant difference between the two groups (P <0.005). Female patients with AMI compared with men, older, with a history of hypertension more, more anterior infarction, serum creatine phosphokinase level is lower, higher blood sugar levels, heart rupture more. These factors may account for the poor prognosis of women with AMI. In addition, multivariate stepwise regression analysis showed that history of angina, blood urea nitrogen, total serum cholesterol and cardiogenic shock were predictors of hospital mortality in women with AMI.