论文部分内容阅读
The fluorocarbanion [n-C_3F_7OCF (CF_3)~-] generated by decarbomethoxylation of methylperfluoro-2-methyl-3-oxa-hexanoate(1)can be trapped in many cases with substituted benzoyl chlorides(YArCOCl). In this way, a simple, convenient method for the preparation of aryl β-oxa-fluoroalkyl-ketones has been developed, The mechanistic consideration of the ester decomposition inducedby the lithium chloride/hexamethylphosphoric triamide complex (LiCl/HMPA) and KI/CH_2CNinvolves nucleophilic attack by halides on the methoxy carbon of the ester 1.
The fluorocarbanion [n-C_3F_7OCF (CF_3) ~]] generated by decarbomethoxylation of methylperfluoro-2-methyl-3-oxa-hexanoate (1) can be trapped in many cases with substituted benzoyl chlorides (YArCOCl) , convenient method for the preparation of aryl β-oxa-fluoroalkyl-ketones has been developed, The mechanistic consideration of the ester decomposition induced by the lithium chloride / hexamethylphosphoric triamide complex (LiCl / HMPA) and KI / CH 2 CNinvolves nucleophilic attack by halides on the methoxy carbon of the ester 1.