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目的就中药应用中出现的不良反应原因进行分析,为避免和减少中药药品不良反应提供参考。方法结合临床实践,并结合文献总结中药及其制剂在使用中发生不良反应的原因。结果与结论长期以来在人民的头脑中形成一个误区认为中药比西药安全,但是任何事物都有它的两面性,使用不当同样会引起不良反应,随着近几年中药研究的进一步发展,中药及其制剂在我国广泛应用,同时也发现了中药不良反应的报道也逐年增多。中药及其制剂在使用中发生不良反应的原因主要表现在以下8个方面。1.品种混乱:在应用的时候不辨真伪,误将混淆品种作为正品使用,引发中毒;2.滥用中药:有些人迷信传说和文献错载,对其中的单方、验方自配自用或江湖医生随意配置中药制剂,质量难以保证;3.过量或用法不当;4.疗程过长:认为中药无毒或毒性小,然而长期使用有毒中药或其制剂,会在体内慢慢积蓄,造成严重后果;5.配伍与用药禁忌不合理;6.炮制失度;7.辨证不准;8.剂型失宜;9.个体差异。
Objective To analyze the causes of adverse reactions in the application of traditional Chinese medicine and to provide reference for avoiding and reducing adverse reactions of traditional Chinese medicines. Methods Combining with clinical practice and combining the literature to summarize the causes of adverse reactions of traditional Chinese medicine and its preparations in use. Results and Conclusions It has long been a misunderstanding in people’s minds that Chinese medicine is safer than Western medicine, but everything has its two sides. Improper use can also cause adverse reactions. With the further development of traditional Chinese medicine research in recent years, traditional Chinese medicine and its The preparations have been widely used in China. At the same time, reports on the adverse reactions of traditional Chinese medicines have also been found to increase year by year. The causes of adverse reactions in the use of traditional Chinese medicine and its preparations are mainly manifested in the following eight aspects. 1. Variety confusion: When the application is not true or false, mistakenly confusing the variety as a genuine use, causing poisoning; 2. Misuse of Chinese medicine: Some people believe that the legend and the literature are misplaced, and the unilateral and self-contained ones are used for personal use or rivers and lakes. Doctors are free to configure traditional Chinese medicine preparations, the quality is difficult to guarantee; 3. excessive or improper use; 4. long course of treatment: that the Chinese medicine is non-toxic or toxic, but long-term use of toxic traditional Chinese medicine or its preparation will slowly accumulate in the body, causing serious consequences 5.5. Constraints on compatibility and medications are unreasonable; 6. Misconducted; 7. Inaccurate dialectic; 8. Improper dosage forms; 9. Individual differences.