论文部分内容阅读
目的 探讨纤维蛋白降解产物 (FDP)、D 二聚体 (D dimer)等指标用于矽肺早期诊断的意义和价值。方法 对无矽肺 0 + 者 ,Ⅰ期矽肺患者进行六项指标的测定。结果 经方差分析 ,0 + 组中铜蓝蛋白 (CP)、血清羟脯氨酸(HYP)、丙二醛 (MDA)、超氧化物歧化酶 (SOD)及FDP均高于正常对照组 ,Ⅰ期组的CP、MDA、HYP、D dimer水平均高于0 + 组。判别分析表明 ,CP、MDA、HYP、D dimer四项指标建立的判别方程与矽肺Ⅰ期X线诊断符合率为 10 0 % ,0 + 为74 1%。结论 D dimer、CP、MDA、HYP可作为矽肺早期诊断的指标。
Objective To investigate the significance and value of fibrinogen degradation products (FDP) and D dimer in the early diagnosis of silicosis. Methods Six indexes of patients without silicosis 0 + and silicosis Ⅰ were measured. Results By ANOVA, the levels of ceruloplasmin (CP), serum hydroxyproline (HYP), malondialdehyde (MDA), superoxide dismutase (SOD) and FDP in 0 + group were higher than those in normal control group The level of CP, MDA, HYP and D dimer in stage group were higher than that in 0 + group. Discriminant analysis showed that the discriminant equations established by the four indexes of CP, MDA, HYP and D dimer coincided with the diagnostic accuracy of silicosis Ⅰ -phase X-ray, and 0 + was 74 1%. Conclusion D dimer, CP, MDA, HYP can be used as indicators of early diagnosis of silicosis.