论文部分内容阅读
目的 探讨新生儿缺氧缺血性脑病CT分期与病理变化、临床病情的一致性 ,以正确指导治疗和估计预后。方法 对 36例有窒息史、无其它疾病的新生儿进行CT扫描 (平扫 ) ,其中 2 1例距第 1次扫描 0 .5～ 2 4月作复扫。结果 全部病例均出现脑水肿 ,13例低密度水肿区内出现更低密度为脑质坏死 ,16例合并蛛网膜下腔出血 ,2例出现脑内灶性出血。复查 2 1例 ,脑水肿者复查 11例 ,8例完全恢复 ,无遗留后遗症 ;10例水肿区内有更低密度者 ,经复查 8例出现脑软化、脑萎缩及发育不良 ,临床上出现不同程度智力落后、脑瘫、癫痫等。结论 HIE的脑损害程度与脑水肿范围大小无明显相关关系 ,主要取决于有无脑质坏死。CT分期有助于与病理、临床一致 ,正确指导治疗和估计预后。
Objective To investigate the CT staging and pathological changes of neonatal hypoxic-ischemic encephalopathy, the consistency of clinical conditions, to guide the correct treatment and prognosis. Methods Thirty-six neonates with asphyxia history and no other diseases were examined by CT scan (plain scan). Among them, 21 cases were retrospectively scanned 0.5 to 2 months after the first scan. Results Cerebral edema occurred in all the cases. In the 13 cases with low density edema, the lower density was cerebral necrosis, 16 cases with subarachnoid hemorrhage and 2 cases with intracerebral hemorrhage. Reexamined 21 cases, 11 cases of brain edema review, 8 cases of complete recovery, no legacy sequelae; 10 cases of lower density within the edema area, the review of 8 cases of brain softening, brain atrophy and dysplasia, clinical differences Degree of mental retardation, cerebral palsy, epilepsy and so on. Conclusions There is no significant correlation between the extent of brain damage and the extent of cerebral edema in HIE, which mainly depends on the presence of cerebral necrosis. CT staging helps with pathology, clinical consistency, correct treatment and prognosis.