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出血性休克及脑病综合征(HSES)时的高热是否在病理生理学上有重要意义尚有争论。外周血中白细胞核呈放射状分裂(即“葡萄状核”)见于成人中暑患者已有报道,并认为是该病的特征。作者曾观察4例年龄为2～4个月的HSES患儿,其中3例有高热及穿衣过多史。所有患儿发病时均有大汗湿透衣服、意识消失、休克及痉挛,其中2例于入院时外周血中检出大量带有葡萄状核的白细胞,这些白细胞于24小时后消失,另2例于起病后18小时才检测血液,未发现此种白细胞。以前在HSES患儿中尚未报道过有此种改变,作者认为于疾病早期注意寻找此种白细胞对HSES诊断
Whether or not hyperthermia in hemorrhagic shock and encephalopathy syndrome (HSES) is pathophysiologically significant remains debatable. Radiation-disrupted leukocytes in the peripheral blood (ie, “grape-like nuclei”) have been reported in adult patients with stroke and are considered to be characteristic of the disease. The authors have observed 4 cases of HSES children aged 2 to 4 months, of whom 3 had hyperthermia and excessive clothing. All children were sweaty clothes, consciousness disappeared, shock and cramps, 2 cases were admitted to the hospital with a large number of peripheral blood leukocytes with grapes nucleus, the white blood cells disappeared after 24 hours, and the other 2 Example 18 hours after the onset of blood tests, did not find such white blood cells. Previously, no such changes have been reported in children with HSES, the authors believe that early in the disease pay attention to find such white blood cells HSES diagnosis