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1980年6～9月,我们采用痢特灵与庆大霉素、四环素与 TMP 联合治疗急性菌痢80例.病例选择均为急性菌痢普通型,年龄18～55岁。服药方法 A 组:痢特灵每次100毫克,每日3次口服;庆大霉素每次8万单位,每日2次肌注。B 组:TMP 每次0.1克,每日2次口服;四环素每次0.5克,每日4次口服。治疗结果 A 组47例,男25例,女22例.32例于治疗后5～10天痊愈,15例于10～13天治愈.(痊愈标准:症状消失,大便镜检正常.)B 组33例,男19例、女14例。25例于治疗后5～10天痊愈,8例于10～15天治愈.两组治愈时间无明显差异.A 组1例无效者加用 TMP 后6天治愈;B 组1例无效者加用庆大霉素后4天亦治愈。治疗过程中,除 A 组1例及 B 组2例出现恶心
From June to September 1980, we adopted the combination of furazolidone and gentamicin, tetracycline and TMP in the treatment of 80 cases of acute bacillary dysentery.All cases were selected as acute common bacillary dysentery, aged from 18 to 55 years. Medication methods Group A: 100 mg of furazolidone, 3 times a day orally; gentamicin 80,000 units each time, 2 times a day intramuscular injection. Group B: TMP 0.1g each time, 2 times a day orally; tetracycline each 0.5g, 4 times a day orally. Results A group of 47 patients, 25 males and 22 females .32 cases cured 5 to 10 days after treatment, 15 cases were cured in 10 to 13 days (recovery criteria: the symptoms disappeared, stool microscopy was normal.) Group B 33 cases, 19 males and 14 females. 25 cases recovered 5 to 10 days after treatment, and 8 cases were cured on days 10 to 15. There was no significant difference between the two groups in the healing time.The patients in group A were cured after 6 days of treatment with ineffective TMP and one case of ineffective in group B 4 days after gentamicin is also cured. During treatment, nausea occurred in 1 patient in group A and 2 patients in group B.