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1 引言类风湿性关节炎(RA)是一种常见的结缔组织疾病,其合并肾损害者常见,但RA本身所致肾小球肾炎(GN),简称RA-GN,较少见,国外文献报道RA患者可出现各种类型肾小球病变,以系膜增生性肾炎为主。国内有关RA肾损害的资料不多,且多无肾活检资料。我科自1987年～2001年9月共收治4例RA肾损害患者,均经肾活检证实,且排除药物所致。本文报告此4例患者的组织病理资料,并结合文献进行复习。 2 材料与方法 4例RA均为我科住院患者,全部符合1987年美国风
1 Introduction Rheumatoid arthritis (RA) is a common connective tissue disease, which is common in patients with renal damage, but RA itself caused by glomerular nephritis (GN), referred to as RA-GN, rare, foreign literature Reported RA patients may have various types of glomerular lesions, mainly mesangial proliferative glomerulonephritis. Domestic information on RA renal damage is small, and more data without renal biopsy. Our department from 1987 to September 2001 were treated 4 RA patients with renal damage, confirmed by renal biopsy, and rule out the drug. This article reports the histopathological data of 4 patients and reviews the literature. 2 Materials and Methods 4 cases of RA are our hospitalized patients, all in line with the 1987 American wind