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目的 研究腹腔镜手术与米非司酮联合治疗卵巢子宫内膜异位囊肿的疗效。方法 2003年 7月至2004年 4月佛山市第一人民医院将 98例腹腔镜下卵巢子宫内膜异位囊肿术后的患者随机分两组:单纯腹腔镜手术组 43例;联合治疗组 55例,术后口服米非司酮 12 5mg连续 3个月。所有患者随访 3 ~12个月。结果 随访率为 94.9% (93 /98)。联合治疗组有效率 61.5%,单纯手术组有效率 46.3%,联合治疗组的疗效明显高于单纯手术组(P<0.05)。服用米非司酮的患者仅有 4例转氨酶轻度升高。结论 腹腔镜术后联合米非司酮治疗优于单纯手术治疗,可以作为卵巢子宫内膜异位囊肿临床治疗选择方案。
Objective To study the efficacy of laparoscopic surgery and mifepristone in the treatment of ovarian endometriosis. Methods From July 2003 to April 2004, 98 cases of laparoscopic ovarian endometriotic cyst in Foshan First People’s Hospital were randomly divided into two groups: 43 cases in simple laparoscopic surgery group and 55 cases in combined treatment group Cases, postoperative oral mifepristone 125mg for 3 months. All patients were followed up for 3 to 12 months. Results The follow-up rate was 94.9% (93/98). The effective rate of combined treatment group was 61.5% and that of simple operation group was 46.3%. The curative effect of combined treatment group was significantly higher than that of simple operation group (P <0.05). Only 4 patients who took mifepristone had mildly elevated aminotransferases. Conclusions Laparoscopic combined with mifepristone treatment is superior to simple surgical treatment, which can be used as clinical treatment options for ovarian endometriosis.