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唇裂的形成是因胚胎发育时中胚叶从神经嵴到头部和面部的增厚支膜复盖不全,移行迟缓或缺如所致。腭裂是因胎儿发育期间裂缝内舌异位,导致腭难以融合。胚胎性腭分为初腭和继发腭二阶段。初腭发育于妊娠4～7周,由门齿骨(四个前齿及其牙槽)、鼻中膈和鼻小柱组成。继发腭发育于妊娠7～12周,包括硬腭和软腭。唇、腭裂按程度可分为:1.不全性腭裂;2.完全性腭裂;3.不全性腭裂及唇裂;4.单侧完全性唇腭裂;5.双侧完全性唇腭
Cleft lip formation is due to embryonic development of the mesoderm from the neural crest to the head and face thickening of the branch of incomplete coverage, migration delay or lack of due. Cleft palate is due to tongue during the development of the fetus during ectopic, leading to difficult to integrate the palate. Embryonic palate is divided into early palate and secondary palate two stages. Early palatal development in pregnancy 4 to 7 weeks, composed of the incisors (four anterior teeth and their alveoli), nasal septum and nasal cartilage. Secondary palatal development in pregnancy 7 to 12 weeks, including the hard palate and soft palate. Cleft lip and palate according to the degree can be divided into: 1. incomplete cleft palate; 2. complete cleft palate; 3. incomplete cleft palate and cleft lip; 4. unilateral complete cleft lip and palate; 5. bilateral complete cleft lip and palate