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为观察人胎儿中枢神经系统（ＣＮＳ）星形胶质细胞（ａｓｔｒｏｃｙｔｅ，Ａｓｔ）形态发育。用胶质原纤维酸性蛋白（ＧＦＡＰ）抗体进行免疫组织化学染色。结果表明：（１）在颈段脊髓、脑干、海马和小脑蚓部于胚胎２５周其ＧＦＡＰ染色强度、细胞密度接近出生时水平。而此时期大脑皮层Ａｓｔ密度约为出生时的四分之一。（２）在同一胎龄ＣＮＳ的不同部位，ＧＦＡＰ阳性Ａｓｔ分布不均匀。（３）Ａｓｔ不仅在毛细血管周围，而且在小血管周围密度大，染色深，环绕血管呈辐射状排列。（４）人胎脑ＧＦＡＰ阳性细胞不具有典型的Ⅰ、Ⅱ型Ａｓｔ特点，可见单突起、少突起、中间型和多突起４种类型。这提示，人胎儿ＣＮＳ星形胶质细胞发育表现为形态上逐渐成熟和数量上逐渐增加，但在ＣＮＳ不同部位存在差别
To observe the morphological development of human fetal central nervous system (CNS) astrocyte (Ast). Immunohistochemical staining with glial fibrillary acidic protein (GFAP) antibody. The results showed that: (1) GFAP staining intensity and cell density at cervical cervical spinal cord, brainstem, hippocampus and cerebellar vermis at embryonic week 25 were close to those at birth. At this stage of cerebral cortex Ast density is about one quarter of birth. (2) The distribution of GFAP-positive Ast in different parts of the same gestational age CNS is not uniform. (3) Ast not only around the capillaries, but also in the small blood vessels around the density, deep staining, arranged radially around the blood vessels. (4) The GFAP positive cells of human fetal brain do not have the typical characteristics of type I and type II Ast. Four types of mono-protrusion, few protrusion, middle type and multiple protrusion can be seen. This suggests that human fetal CNS astrocytes develop morphologically gradually mature and quantitatively increased, but there are differences in different parts of the CNS