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1836年首次报道多发性硬化(MS)病例以来,至今其病因仍未阐明。曾提出过多种假说,如:感染、自身免疫等,但均未被人们所普遍接受。今就有关MS的病毒致病学说的研究作一次回顾。很多疾病的病因是从流行病学研究中找到的,对MS进行的大量流行病学研究工作均表明:MS的发病年龄高峰在30岁左右,15岁以下和55岁以上的人群中很少发生,MS的地理分布有明确的特点:北欧、加拿大、北美、澳大利亚南部、新西兰为高发区,发病率达
The first reported case of multiple sclerosis (MS) in 1836, the etiology has so far not been elucidated. Various hypotheses have been proposed, such as infection and autoimmunity, but none of them have been universally accepted. A review of the studies on the viral pathogenesis of MS has now been made. The etiology of many diseases is found in epidemiological studies, a large number of epidemiological studies conducted on MS have shown that the peak age of onset of MS is around the age of 30, seldom occurs in people under 15 and over 55 , The geographical distribution of MS has definite characteristics: northern Europe, Canada, North America, southern Australia, New Zealand is a high incidence area, the incidence of up to