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目的探讨伴肝功能损害的痛性糖尿病神经病变患者镇痛药物的选择。方法临床药师参与1例痛性糖尿病神经病变患者的治疗过程,通过分析病情对镇痛药物的选择提出监护建议。结果患者同时伴有肝功能损害,临床药师建议选择普瑞巴林镇痛治疗,根据治疗效果调整剂量。治疗后患者的疼痛程度逐渐减轻、发作次数减少,症状有明显缓解。结论普瑞巴林是痛性糖尿病神经病变合并肝功能损害患者合适的选择,临床药师通过分析并设计给药剂量和频次,缓解患者的痛苦,保障用药安全,体现出药师的价值。
Objective To investigate the choice of analgesic drugs for painful diabetic neuropathy with liver dysfunction. Methods Clinical pharmacists participated in the treatment of one patient with painful diabetic neuropathy, and proposed the guardianship recommendations by analyzing the choice of analgesic drugs. Results Patients with liver dysfunction, the proposed choice of clinical pharmacists pregabalin analgesic treatment, according to the therapeutic effect of adjusting the dose. After treatment, patients gradually reduce the degree of pain, reduce the number of attacks, symptoms were significantly alleviated. Conclusions Pregabalin is a suitable choice for patients with painful diabetic neuropathy complicated with liver dysfunction. Clinical pharmacists analyze and design the dosage and frequency of administration to relieve the patient’s pain, ensure the safety of medication and reflect the value of pharmacists.