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目的:研究分析四会市2003-2005年恶性肿瘤及鼻咽癌患者的生存状况,为预后评价和防治提供依据。方法:1 665例登记病例的生存情况随访截止日期为2010-12-31。数据应用SPSS 17.0进行统计分析,乘积限法计算观察生存率,Log-rank检验比较不同年龄组和性别的肿瘤生存率。结果:四会市2003-2005年5年观察生存率位于前5位的恶性肿瘤分别为子宫体肿瘤(68.8%)、乳腺癌(63.5%)、甲状腺癌(63.2%)、卵巢癌(58.8%)和鼻咽癌(55.6%),后5位分别是肝癌(3.8%)、食管癌(4.2%)、肺癌(5.3%)、骨肿瘤(5.9%)以及胆道和胰腺癌(11.1%)。<40岁患者的5年观察生存率为38.0%,40～<50岁为30.3%,50～<60岁为25.5%,≥60岁为14.1%。男、女恶性肿瘤的5年观察生存率分别是18.3%和33.2%。鼻咽癌患者的5年观察生存率从1971-1976年的20.4%明显提高到2003-2005年的55.6%。结论:随着年龄的增加,肿瘤患者生存率下降;女性患者的肿瘤生存率高于男性。四会市鼻咽癌的5年生存率呈现逐年升高的趋势。
Objective: To study the survival status of patients with malignant tumor and nasopharyngeal carcinoma from 2003 to 2005 in Sihui City, and to provide evidence for prognosis evaluation and prevention. Methods: The survival of 1 665 cases was followed up for 2010-12-31. The data were analyzed by SPSS 17.0, the survival rate was calculated by the product limit method, and the survival rates of different age groups and genders were compared by Log-rank test. Results: The top 5 malignant tumors in Sihui City in the five years from 2003 to 2005 were 68.8%, 63.5%, 63.2%, 58.8% ) And nasopharyngeal carcinoma (55.6%). The last five were liver cancer (3.8%), esophageal cancer (4.2%), lung cancer (5.3%), bone tumor (5.9%) and biliary tract and pancreatic cancer (11.1%). The 5-year survival rate was 38.0% in patients <40 years of age, 30.3% in patients 40- <50 years, 25.5% in patients 50-60 years and 14.1% in those 60 years of age. The 5-year survival rates of male and female malignant tumors were 18.3% and 33.2%, respectively. The 5-year survival rate of patients with NPC was significantly increased from 20.4% in 1971-1976 to 55.6% in 2003-2005. Conclusion: With the increase of age, the survival rate of cancer patients decreased; the survival rate of female patients was higher than that of males. Sihui City, 5-year survival rate of nasopharyngeal carcinoma showed an upward trend year by year.