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目的探讨妊娠合并梅毒的临床特点及对母婴结局的影响。方法回顾性分析采用疝环充填式无张力疝修补术治疗的60例腹股沟斜疝患者的临床资料。结果梅毒组的早产率、流产率及死胎率均高于健康对照组,两组比较有显著性差异(P<0.01);治疗组的先天性梅毒儿发生率及围生儿死亡率均明显低于未治疗组,两组比较有显著性差异(P<0.01)。结论应对孕产妇进行梅毒螺旋体血清学检验,对确诊为妊娠合并梅毒的患者应尽早采取规范治疗措施,以改善妊娠结局及围生儿预后。
Objective To investigate the clinical features of syphilis during pregnancy and its effect on maternal and infant outcomes. Methods The clinical data of 60 patients with inguinal hernia treated with hernia ring filling tension-free hernia repair were retrospectively analyzed. Results The preterm birth rate, miscarriage rate and stillbirth rate in syphilis group were higher than those in healthy control group, with significant difference between the two groups (P <0.01). The incidence of congenital syphilis and perinatal mortality in the treatment group were significantly lower In the untreated group, there was a significant difference between the two groups (P <0.01). Conclusion Treponema pallidum serological test should be conducted on pregnant women, standardized treatment for patients diagnosed with pregnancy complicated with syphilis should be taken as soon as possible to improve the pregnancy outcome and perinatal outcome.