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目的:评估新生儿缺氧缺血性脑病(HIE)CT表现与临床疗效。材料与方法:通过对97例新生儿HIE低密度灶不同脑叶分布及其CT值变化并结合其中46例不同时期随访表现进行分折。结果:97例新生儿HIE分布于不同脑叶的低密度灶共301个,其CT值在25Hu-12Hu之间,与非病变区脑组织密度及对照组的正常脑组织密度具有显著性差异(P<0.05)。本组资料显示HIE低密度灶明显集中于额叶及颞叶;枕叶及顶叶较少。46例不同时期随访的CT检查显示位于颈叶、颈叶较小病灶吸收恢复时间明显早于枕叶及顶叶,其中较大面积的低密度灶恢复时间要长且有可能形成更低密度的脑软化灶(CT值<15Hu)。结论:新生儿HIE低密度灶出现于顶叶或枕叶其恢复时间要长于颞叶及额叶,较大面积的低密度灶(10mm-15mm)有可能形成脑软化灶并导致相应的临床症状出现。
Objective: To evaluate CT findings and clinical effects of neonatal hypoxic-ischemic encephalopathy (HIE). Materials and Methods: 97 cases of neonatal HIE low density lesions of different lobar distribution and CT value changes and combined with 46 cases of different periods of follow-up performance analysis. Results: A total of 301 neonates with HIE were found in 301 low-density lesions with different lobes. The CT values were between 25 and 12 uu, which were significantly different from those in non-diseased areas (P <0.05) P <0.05). This group of data show that HIE low density lesions were significantly concentrated in the frontal and temporal lobes; less occipital and parietal lobes. 46 cases of different stages of follow-up of CT examination showed that the lesion in the neck and cervical lesion absorption recovery time significantly earlier than the occipital and parietal lobes, including large areas of low density lesions recovery time is longer and may form a lower density Cerebral softening (CT value <15Hu). Conclusion: HIE low density lesions in the parietal lobe or occipital lobe recovery time longer than the temporal lobe and frontal lobe, a large area of low density lesions (10mm-15mm) may form cerebral softening and lead to the corresponding clinical symptoms appear.