【摘 要】
：
用免疫组织化学方法及单克隆抗体ＣＤ４、ＣＤ８、ＣＤ３、Ｉ２、Ｔａｃ对３０例ＧＤ患者和２２例ＨＴ患者甲状腺内浸润淋巴细胞进行观察。结果表明ＧＤ或ＨＴ的甲状腺内ＣＤ＋４Ｔ细胞数量均高于ＣＤ８＋Ｔ细胞；ＨＴ甲状腺内ＣＤ８＋Ｔ细胞、Ｉ２＋细胞、Ｔａｃ＋细胞百分数量显著高
【机 构】
：
西安医科大学第一附属医院内分泌科, 西安医科大学病理解剖学教研室
论文部分内容阅读
用免疫组织化学方法及单克隆抗体ＣＤ４、ＣＤ８、ＣＤ３、Ｉ２、Ｔａｃ对３０例ＧＤ患者和２２例ＨＴ患者甲状腺内浸润淋巴细胞进行观察。结果表明ＧＤ或ＨＴ的甲状腺内ＣＤ＋４Ｔ细胞数量均高于ＣＤ８＋Ｔ细胞；ＨＴ甲状腺内ＣＤ８＋Ｔ细胞、Ｉ２＋细胞、Ｔａｃ＋细胞百分数量显著高于ＧＤ甲状腺内相应细胞的百分数量。活化的淋巴细胞与血中ＴＧＡ和ＭＣＡ水平呈显著正相关。结合ＧＤ与ＨＴ的病理改变，提示ＨＴ甲状腺内免疫反应较ＧＤ时更为激烈，ＣＤ８＋Ｔ细胞在ＨＴ中的作用可能更为重要，甲状腺活化的淋巴细胞与自身抗体产生具有密切关系。
Immunohistochemistry and monoclonal antibodies CD4, CD8, CD3, I2, Tac in 30 patients with GD and 22 patients with thyroid infiltration of lymphocytes were observed. The results showed that the number of CD + 4T cells in thyroid of GD or HT was higher than that of CD8 + T cells. The percentages of CD8 + T cells, I2 + cells and Tac + cells in HT thyroid were significantly higher than that in GD thyroid. Activated lymphocytes and blood TGA and MCA levels were significantly positive correlation. Combined with the pathological changes of GD and HT, it is suggested that the immune response in HT is more intense than that in GD. The role of CD8 + T cells in HT may be more important. Thyroid activated lymphocytes are closely related to the production of autoantibodies.
其他文献
根據社會發展規律,一切都是進步的,那麼中醫也不能例外。中國具有數千年悠久歷史、有豐富的臨床經驗,在廣大羣眾中,曾解决了許許多多疾病問題,在學術方面是有很多符合科學地
原发性骨质疏松症是一个十分严重的社会问题，困扰很多中老年人的健康。我院自１９９３年５月以来，对９０例女性绝经期后的妇女进行双能量骨密度检查，同时对其中３４例患者进行血雌激素、降钙素、甲
泰山,五岳之首。古迹名胜,久闻天下。每当列车途经泰安,旅客们总是凭窗远眺,翘首东望,以倾慕崇敬的心情注视着一座座雄伟的峰峦。中外旅游者如有机会登泰山、上南天门,一览
The graphene-based semi-solid grease with low friction coefficient was prepared by highly dispersed mixing method.The friction testing result showed that the fr
Catalytically active, stable, and mechanically durable solid K/Al2O3 catalysts for the transesterifica-tion of rapeseed oil with methanol was studied. In a batc
From September 4 to 6,“Rubber Industry Ⅰ& M High-end Forum and 2012 CHINA RUBBER Magazine Annual Conference” was held in Chengdu, Sichuan Province. Fan Rende
粗天然气中毒４一ＤＭＡＰ急救效果观察涂强，叶自煊，余争平，欧阳子倩据一般含硫气田测定，未经脱硫处理的粗天然气中，硫化氢含量中位数为３６．４６ｍｇ／Ｌ超过人的致死浓度。因此，在油田作业中因意外事故而使粗
Die Eigenschaften jeder Methode sind nattirlich verschieden.Die Horizontaliniensind mehr geeignet fuer topographische Karte, waehrend die Hoehenschichten fuer
相对传统的燃油汽车,新能源汽车的安全问题涉及哪些?现在电动车的安全水平还要多少年才能比得上汽车?传统汽油发动机汽车上的安全技术,是不是可以全部复制到新能源汽车?这些
不久前,读了汪向荣先生校注的《唐大和上东征传》,获益良多.但是,书中关于鉴真东渡时所携带的食品“捻头”、“牛苏”均注了“不详”二字.这又使人稍稍感到不太满足.其实,“