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目的探讨高频电刀(LEEP)在宫颈上皮内瘤变(CIN)诊治中的价值。方法回顾性分析2007年6月-2010年12月在皖北煤电集团总医院门诊就诊的宫颈上皮内病变患者78例,上述患者术前均按照宫颈病变诊疗三阶梯法,先行细胞学检查,有异常者行阴道镜检查或HPV检查,不满意者或HPV阳性者行阴道镜下多点活检确诊为CIN后,自愿接受LEEP治疗,术后均行病理诊断。结果 LEEP术后病理结果与阴道镜下多点活检病理符合率为79.2%,前者较后者病理结果有轻有重,6例CIN患者LEEP术后病理结果轻于阴道镜下活检病理结果,11例重于阴道镜下活检病理结果,其中2例CINⅢ诊断为宫颈早期浸润癌,3例CINⅡ诊断为CINⅢ。结论 LEEP可诊断和治疗CIN及宫颈原位癌,即可起到阻止浸润癌的发生,又增加了对已患浸润癌的发现率,且安全、有效、并发症少,能保留患者的生育能力,具有很好的诊断和治疗价值。
Objective To investigate the value of high frequency electric knife (LEEP) in diagnosis and treatment of cervical intraepithelial neoplasia (CIN). Methods A retrospective analysis of 78 cases of cervical intraepithelial lesions in Wanbei Coal and Metallurgical Group General Hospital from June 2007 to December 2010 were retrospectively analyzed. Patients with abnormal colposcopy or HPV examination, unsatisfactory or HPV-positive colposcopy multi-point biopsy diagnosed as CIN, the voluntary acceptance of LEEP treatment, postoperative pathological diagnosis. Results The pathological results of LEEP and colposcopy multi-point biopsy coincidence rate was 79.2%, the former was lighter than the latter pathological results, 6 cases of CIN LEEP postoperative pathological results were lighter than colposcopic biopsy results, 11 Cases heavier than colposcopy biopsy results, including 2 cases of CIN Ⅲ diagnosis of early invasive carcinoma of the cervix, 3 cases of CIN Ⅱ diagnosis of CIN Ⅲ. Conclusion LEEP can diagnose and treat CIN and cervical carcinoma in situ, which can prevent the occurrence of invasive carcinoma and increase the detection rate of invasive carcinoma, which is safe, effective and has fewer complications. It can keep the patient’s fertility , Has a good diagnostic and therapeutic value.