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作者应用放射免疫方法，检测了５２例肺癌病人血清及支气管肺泡灌洗液中透明质酸和层粘蛋白的水平，以１１例肺炎病人作对照。结果：肺癌组血清透明质酸和层粘蛋白水平明显高于肺炎组（Ｐ＜０．０５）；肺癌组支气管肺泡灌洗液中透明质酸明显高于肺炎组（Ｐ＜０．０５），而层粘蛋白则与肺炎组无差别。结果提示，血清透明质酸与层粘蛋白及支气管肺泡灌洗液透明质酸与层粘蛋白和支气管肺泡灌洗液透明质酸的高水平是对肺癌诊断有价值的指标。
The authors applied radioimmunoassay to detect the levels of hyaluronic acid and laminin in serum and bronchoalveolar lavage fluid from 52 patients with lung cancer. 11 patients with pneumonia were used as controls. Results: Serum levels of hyaluronic acid and laminin were significantly higher in the lung cancer group than in the pneumonia group (P<0.05). Hyaluronic acid in the bronchoalveolar lavage fluid was significantly higher in the lung cancer group than in the pneumonia group (P<0.05). Laminin was no different from the pneumonia group. The results suggest that high levels of serum hyaluronic acid, laminin, and bronchoalveolar lavage fluid, hyaluronic acid, laminin, and bronchoalveolar lavage fluid are valuable indicators for the diagnosis of lung cancer.