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目的观察磷酸奥司他韦颗粒用于治疗小儿手足口病的临床效果。方法选取医院确诊收治的小儿手足口病患儿124例作为研究对象,随机分为对照组和观察组,每组62例。对照组给予利巴韦林进行治疗,观察组在对照组基础上辅助磷酸奥司他韦颗粒进行治疗,观察2组患儿的临床治疗效果。结果观察组治疗总有效率为96.8%,高于对照组的82.3%,差异有统计学意义(P<0.05)。结论抗病毒唾液酸酶控制剂磷酸奥司他韦颗粒用于辅助治疗小儿手足口病具有显著的临床效果,值得推广应用。
Objective To observe the clinical effect of oseltamivir phosphate granules for the treatment of hand-foot-mouth disease in children. Methods A total of 124 children with HFMD in our hospital were selected as study subjects and randomly divided into control group and observation group with 62 cases in each group. The control group was given ribavirin for treatment. The observation group was given the assistant oseltamivir phosphate on the basis of the control group, and the clinical effect of the two groups was observed. Results The total effective rate of observation group was 96.8%, higher than 82.3% of control group, the difference was statistically significant (P <0.05). Conclusion The anti-virus sialidase inhibitor oseltamivir phosphate granules has significant clinical effect in adjuvant treatment of hand-foot-mouth disease in children and is worth popularizing.