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我院儿保科与产科协作,对出生缺陷进行监测,现将调查结果分析如下: 一、调查结果:自1982年至1986年,5年中共出生7884个婴儿,其中164例共有畸形205个。按人头计出生缺陷发病率为20.80‰,按畸形数计发病率为26.00‰。单一畸形134例,多发畸形30例。出生缺陷按系统或部位的分布见表。城市出生儿缺陷发生率为21.50‰;农村为19.34‰、男22.90‰;女18.60‰。城乡、男女的发病率差异均不显著。不同季节发病率也无明显差异。二、致畸原因分析1.家族畸形史5978名正常儿中有家庭畸形史者38例,占0.6%;164例畸形儿中有家庭畸形史者9例,占5.5%,二者相差9倍(P<0.01)。其中产妇连续2胎均有畸形者4例,且第二个畸形儿更严重。
Our hospital pediatrics and obstetrics collaboration, monitoring of birth defects, the findings are as follows: First, the survey results: from 1982 to 1986, 5,866 births were born in the Chinese Communist Party, of which 164 cases had a total of 205 deformities. The incidence of birth defects by head count was 20.80 ‰, according to the number of deformities incidence of 26.00 ‰. A single deformity in 134 cases, multiple deformities in 30 cases. Birth defects according to the distribution of the system or part of the table. The incidence of urban birth defects was 21.50 ‰; 19.34 ‰ in rural areas, male 22.90 ‰; female 18.60 ‰. The incidence of urban and rural areas, men and women were not significantly different. The incidence of different seasons there was no significant difference. Second, the causes of teratogenicity 1. Family history of malformations 5978 normal children in 38 cases of family history of malformations, accounting for 0.6%; 164 cases of deformity in children with family history of malformations in 9 cases, accounting for 5.5%, a difference of 9 times (P <0.01). Among them, 2 consecutive mothers were malformed in 4 cases, and the second deformity was more serious.