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目的探讨抗核抗体在自身免疫性疾病中的应用。方法收集我院血液内科、内分泌科、肝病科2014年10月-2015年10月100例初治自身免疫性疾病患者,分为试验组;40例我院体检科健康志愿者,分为对照组。收集所有患者清晨空腹静脉血4ml,离心取血清进行抗核抗体(ANA)检测。结果试验组ANA检测阳性总人次为64人,总检出率64%。其中SS ANA检出6人次,检出率60%;PBC ANA检出12人次,检出率100%;RA ANA检出12人次,检出率30%;SLE ANA检出34人次,检出率89.47。结论 ANA的检出率在自身免疫病的诊断中有重要的意义,但为非特异性的指标。
Objective To investigate the use of antinuclear antibodies in autoimmune diseases. Methods A total of 100 patients with newly diagnosed autoimmune diseases in our hospital from October 2014 to October 2015 were enrolled in this study. They were divided into experimental group and 40 healthy volunteers in our hospital. The patients were divided into control group . All patients were collected fasting venous blood 4ml, centrifuged serum for anti-nuclear antibody (ANA) test. Results The total positive rate of ANA in test group was 64, with a total detection rate of 64%. Among them, SS ANA was detected 6 times, the detection rate was 60%; PBC ANA detected 12 passengers, the detection rate was 100%; RA ANA detected 12 passengers, the detection rate was 30%; SLE ANA detected 34 passengers, the detection rate 89.47. Conclusion The detection rate of ANA is important in the diagnosis of autoimmune diseases, but it is a nonspecific index.