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目的评价腺苷蛋氨酸联合谷胱甘肽治疗慢性乙型肝炎的效果。方法50例慢性乙型肝炎患者随机分为对照组和观察组,对照组采用甘利欣常规治疗,观察组采用腺苷蛋氨酸联合谷胱甘肽治疗。结束后对两组患者的临床效果进行比较。结果观察组临床总有效率为76.00%,高于对照组的临床总有效率48.00%,具有显著差异(χ2=4.1596,P<0.05);观察组治疗后T-BiL为(98.4±15.5)μmol/L、ALT为(86.2±11.6)U/L均低于对照组治疗后的(154.2±11.6)μmol/L、ALT(123.4±16.5)U/L,具有显著差异(P<0.001)。结论腺苷蛋氨酸联合谷胱甘肽治疗慢性乙型肝炎疗效佳,而且也安全,建议临床进一步推广。
Objective To evaluate the effect of adenosine methionine combined with glutathione on chronic hepatitis B. Methods Fifty patients with chronic hepatitis B were randomly divided into control group and observation group. The control group was treated with Glycyrrhizin and the observation group was treated with adenosyl methionine and glutathione. After the end of the two groups of patients to compare the clinical effects. Results The total clinical effective rate in observation group was 76.00%, which was significantly higher than that in control group (48.00%) (χ2 = 4.1596, P <0.05). The T-BiL in observation group was (98.4 ± 15.5) μmol / L and ALT of (86.2 ± 11.6) U / L were significantly lower than those of control group (154.2 ± 11.6) μmol / L and ALT (123.4 ± 16.5) U / L, respectively. Conclusion adenosine methionine combined with glutathione in the treatment of chronic hepatitis B has a good effect, but also safe, it is recommended to further promote the clinical.