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目的：：探究正确的护理方式对于雾化吸入联合无创正压通气治疗COPD合并Ⅱ型呼吸衰竭的临床效果。方法：60例COPD合并Ⅱ型呼吸衰竭实施雾化吸入联合无创正压通气，并实施优质护理，2周后患者的治疗效果及血气指标。结果：总体有效率为96.7%，血气指标明显改善，较治疗前存在明显差异性，具有统计学意义。结论：雾化吸入联合无创正压通气治疗COPD合并Ⅱ型呼吸衰竭疗效确切，加之优质护理可明显改善患者预后，提高患者的生存率。“,”Objective: To explore the proper way to care for inhalation combined noninvasive positive pressure ventilation in COPD patients with type Ⅱ respiratory failure clinical results. Methods: 60 COPD patients with type Ⅱ respiratory failure inhalation joint implementation of noninvasive positive pressure ventilation, and implement quality care, treatment and blood gas analysis in patients after 2 weeks. Results: The overal response rate was 96.7%, significantly improved blood gas analysis, there are significant differences compared with before treatment, with statistical significance. Conclusion: inhalation combined noninvasive positive pressure ventilation in COPD Patients with Type Ⅱ respiratory failure efficacy, combined with high-quality care can significantly improve the prognosis of patients, improve the survival rate of patients.