论文部分内容阅读
目的:探讨分析高同型半胱氨酸血症与心肌梗死的关系。方法:对2013年3月~2015年3月期间我院收治的50例心肌梗死患者及同期在我院进行健康体检的50例健康人的临床资料进行回顾性研究。我们将这50例心肌梗死患者设为观察组,将同期在我院进行健康体检的50例健康人设为对照组。在对观察组患者进行治疗前后,分别对其血清Hcy(同型半胱氨酸)的水平进行检测。同时,统计观察组患者中存在吸烟史、饮酒史患者的人数及患有高血压、高脂血症患者的人数。并使用条件Logistic回归模型对导致这些患者发生心肌梗死的原因进行分析。结果:在进行治疗前,观察组患者血清Hcy的水平明显高于对照组的健康人,二者相比差异具有显著性(P<0.05)。进行治疗后,观察组患者血清Hcy的水平明显低于进行治疗前的水平,二者相比差异具有显著性(P<0.05)。结论:高同型半胱氨酸血症是导致心肌梗死的危险因素,此病与心肌梗死的发生密切相关。因此,在临床上应加强对高同型半胱氨酸血症的研究与治疗。
Objective: To investigate the relationship between hyperhomocysteinemia and myocardial infarction. Methods: The clinical data of 50 patients with myocardial infarction admitted in our hospital from March 2013 to March 2015 and 50 healthy people in our hospital during the same period were retrospectively studied. We set the 50 cases of myocardial infarction as observation group, the same period in our hospital for physical examination of 50 healthy subjects as a control group. Before and after the treatment of observation group patients, respectively, the level of serum Hcy (homocysteine) were detected. At the same time, the number of patients with smoking history, drinking history and the number of patients with hypertension and hyperlipidemia were observed in the observation group. Conditional logistic regression models were used to analyze the causes of myocardial infarction in these patients. Results: Before treatment, the level of Hcy in observation group was significantly higher than that in control group (P <0.05). After treatment, the level of serum Hcy in observation group was significantly lower than that before treatment, the difference was significant (P <0.05). Conclusion: Homocysteinemia is a risk factor for myocardial infarction. The disease is closely related to the occurrence of myocardial infarction. Therefore, in the clinical should strengthen the research and treatment of hyperhomocysteinemia.