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为了探讨卵巢内胚窦瘤的临床表现、治疗及预后,回顾性分析1989-03-2007-03我院收治的11例卵巢内胚窦瘤患者的临床及病理资料。11例患者均行手术治疗,4例Ⅰ期患者手术时保留了生育功能。10例术后辅以BEP、BVP等方案化疗。随访至2009-06,3例失访,2例死亡,6例健在且无复发及转移。2及5年生存率分别为87.5%(7/8)及83.3%(5/6)。初步研究结果提示,卵巢内胚窦瘤早期患者只要对侧卵巢和子宫正常,可行保留生育功能手术,术后辅以BEP或BVP为主的化疗,治疗效果较好。
In order to explore the clinical manifestations, treatment and prognosis of ovarian endodermal sinus tumor, the clinical and pathological data of 11 patients with ovarian endodermal sinus tumor who were admitted to our hospital from March 1989 to March 2007 were retrospectively analyzed. Eleven patients underwent surgical treatment, and four patients with stage Ⅰ retained fertility during surgery. Ten cases were supplemented with BEP and BVP chemotherapy. Follow-up to 2009-06, 3 cases were lost to follow-up, 2 died, 6 cases were alive without recurrence and metastasis. The 2-year and 5-year survival rates were 87.5% (7/8) and 83.3% (5/6), respectively. Preliminary findings suggest that early ovarian endodermal sinus tumor as long as the contralateral ovary and uterus normal, feasible to retain fertility surgery, postoperative supplemented with BEP or BVP-based chemotherapy, the treatment effect is better.