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心肌梗死所致的细胞丢失、瘢痕形成和心室重构是影响心脏功能的主要因素,也是导致顽固性心力衰竭的病理基础。目前的药物治疗、介入治疗及冠脉旁路手术能够改善心肌缺血,但却不能逆转已经坏死的心肌,而心脏移植的供体少、费用高及慢性排异反应等缺点也限制了其临床应用。近年来
Myocardial infarction caused by cell loss, scarring and ventricular remodeling is the main factor affecting cardiac function, but also lead to pathological basis of refractory heart failure. The current drug therapy, interventional therapy and coronary artery bypass surgery can improve myocardial ischemia, but it can not reverse the necrosis of the myocardium, and heart transplantation less donor, high cost and chronic rejection reaction shortcomings also limits its clinical application. In recent years