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Simple, efficient and convenient synthesis of aminomethylene bisphsophonic acid derivatives in one-pot reaction using aldehydes, hydroxylamine hydrochloride, phosphours trichloride and water as starting materials in the presence of pyridine was described.
Simple, efficient and convenient synthesis of aminomethylene bisphsophonic acid derivatives in one-pot reaction using aldehydes, hydroxylamine hydrochloride, phosphors trichloride and water as starting materials in the presence of pyridine was described.