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我们于1963年9月至1964年2月间共治疗水痘52例,其中10例全身症状和体征较轻微,仅用一般治疗(1%龙胆紫外涂)作对照,余42例为维生秦 B_(12)治疗组,用量为:3岁以下30~50微克,3~8岁用50~100微克,每日一次肌肉注射,直至皮疹干燥结痂为止。治疗组42例临床表现发热24例,瘙痒36例,均有皮疹(大多为斑丘疹,其中36例并存疱疹,1/3病例有粘膜疹),4例有上呼吸道感染症状且咽部充血并有水痘疹。对照组10例全身症状轻微,仅有各期皮疹及瘙痒,仅个别有粘膜疹。治疗组在应用维生素 B_(12)后4/5病例在12~48小时止痒,绝大多数(90%)不再出现皮疹,斑丘疹不再形成疱疹,已有疱疹者在12~24小时内开始结痂,粘膜疹在2~3天内消失,形成溃疡者在2
We treated 52 cases of chickenpox from September 1963 to February 1964, of which 10 had mild symptoms and signs of systemic disease. Only general treatment (1% gentian violet coating) was used as a control. The remaining 42 cases were treated with Vitamin Q B_ (12) treatment group, the amount of: 30 to 50 micrograms below the age of 3, 3 to 8 years old with 50 to 100 micrograms, once daily intramuscular injection, until the rash dry scab so far. In the treatment group, 42 cases had clinical manifestations of fever in 24 cases, pruritus in 36 cases, all had skin rashes (mostly rash, 36 with herpes and 1/3 with mucosal rash), 4 with upper respiratory tract infection and throat congestion There are chickenpox rash. The control group of 10 patients with mild symptoms, only the rash and itching, only a few mucosal rash. The treatment group in the application of vitamin B_ (12) 4/5 cases in 12 to 48 hours itching, the vast majority (90%) no longer appear rash, rash no longer form herpes, herpes have been in 12 to 24 hours Scab began within the mucosal rash disappeared in 2 to 3 days, the formation of ulcers in 2