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目的:评价通过心包内血管处理行肺切除术治疗中晚期肺癌的临床疗效。方法:2006年4月—2011年4月在本院接受心包内血管处理肺切除术的130例中晚期肺癌患者,观察术后并发症和手术死亡率,并分析不同病理分型和TNM分期对生存的影响。结果:手术死亡率为0.77%(1/130),术后并发症发生率为14.6%(19/130)。全组患者的1、3和5年生存率分别为75%、43%和20%。行肺叶切除患者的1、3和5年的生存率均高于全肺切除患者(P<0.01)。行心包内血管处理左肺全切术患者的1、3和5年的生存率要高于心包内右肺全切术后患者(P<0.01)。结论:通过心包内血管处理行肺切除术治疗中晚期肺癌可增加手术切除范围并提高手术切除率,改善患者的术后生存。
OBJECTIVE: To evaluate the clinical efficacy of pneumonectomy and percutaneous transhepatic pneumonectomy in the treatment of advanced lung cancer. METHODS: From April 2006 to April 2011, 130 patients with advanced lung cancer received pericardial pneumonectomy underwent pneumonectomy in our hospital. The postoperative complications and operative mortality were observed. The pathological types and TNM stage were analyzed. The impact of survival. Results: The operative mortality was 0.77% (1/130) and the postoperative complication rate was 14.6% (19/130). The 1, 3 and 5-year overall survival was 75%, 43% and 20% for all patients. The 1,3 and 5 year survival rates of patients undergoing lobectomy were significantly higher than those of patients undergoing pneumonectomy (P <0.01). The 1, 3, and 5-year survival rates were significantly higher in patients who underwent left-sided pneumonectomy with pericardium than those in the pericardium (P <0.01). CONCLUSIONS: Percutaneous transhepatic pneumonectomy for the treatment of advanced lung cancer can increase the range of surgical resection and improve the surgical resection rate and improve the postoperative survival.