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CD44作为一种分布十分广泛的细胞表面粘附分子 ,参与多种肿瘤的浸润和转移过程 ,在多种肾脏恶性肿瘤细胞上也有其多个亚型不同程度的异常表达 ,有研究显示CD44与多种肾脏恶性肿瘤的进展、复发及其诊断的恶性程度有密切相关。
As a widely distributed cell surface adhesion molecule, CD44 participates in the infiltration and metastasis of many kinds of tumors. CD44 also has abnormal expression of many subtypes in many kinds of renal malignant cells. Some studies have shown that CD44 and many The progress of malignant nephropathy, relapse and the diagnosis of malignancy are closely related.