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孤立性纤维性肿瘤(SFT)代表了一种间叶性肿瘤的谱系,包括之前被称为血管外皮细胞瘤的肿瘤。典型的SFT是由大量多形性梭形细胞和胶原纤维组成,呈随意或短束状排列。2002年WHO分类将其归类为中间生物学行为的肿瘤(很少发生转移)。然而,众所周知SFT的临床行为较难预测,无统一的恶性标准,无免疫组化和分子标记指导预后。鲜有报道分析大量原发性SFT的临床病理特征并进行适当统计。因此,作者收集110例SFT(其中79例发生在软组
Solitary fibrous tumors (SFTs) represent a lineage of mesenchymal tumors, including tumors previously known as hemangiopericytomas. A typical SFT is composed of a large number of pleomorphic spindle cells and collagen fibers, arranged randomly or in short bundles. The WHO classification in 2002 classified it as a tumor of intermediate biological behavior (metastasis rarely occurs). However, it is well-known that the clinical behavior of SFT is more difficult to predict, there is no uniform malignancy, and no immunohistochemistry and molecular markers guide the prognosis. Few reports have analyzed the clinical and pathological features of large numbers of primary SFTs and performed appropriate statistics. Thus, the authors collected 110 SFTs (79 of which occurred in the soft group