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有人提出血清α-L-岩藻糖苷酶(AFU)活力是HCC的标志,作者检测了日本人HCC患者血清AFU活力。 病人与方法:研究包括HCC患者67例;肝硬化47例;以健康志愿者54例作对照。67例HCC患者经皮下细针抽吸活检或血管造影确诊,合并有肝硬化。肝硬化患者经超声波和实验室检查随访6月以上排除HCC。每一患者及健康志愿者均作ICG潴留试验、AFP、去γ-羧基凝血酶原、常规肝功能检查。血清AFU活力采用改良的Zielke的方法测定。各项结果以平均±SD表示。
It has been suggested that serum alpha-L-fucosidase (AFU) activity is a hallmark of HCC, and the authors tested serum AFU activity in Japanese HCC patients. Patients and Methods: The study included 67 patients with HCC, 47 patients with cirrhosis, and 54 healthy volunteers as controls. 67 patients with HCC were diagnosed by subcutaneous needle aspiration biopsy or angiography, with cirrhosis. Patients with liver cirrhosis who underwent ultrasound and laboratory tests were followed for more than 6 months to exclude HCC. All patients and healthy volunteers performed ICG retention test, AFP, de-gamma-carboxy prothrombin, and routine liver function tests. Serum AFU activity was determined using the modified Zielke method. Each result is expressed as mean ± SD.