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本文报道了1例异基因骨髓移植(BMT)后复发的ph~+急性髓性白血病(AML)伴t(7;11)病例。患者,女,20岁。因持续高热、咳嗽、贫血、白细胞增多和血小板减少住院。体检:重度贫血,但淋巴结、肝脾均未触及。Hb40g/L,WBC31.3×10~9/L,幼稚细胞56％,血小板0.8×10~9/L。骨髓增生明显活跃,白血病细胞占69.4％,可见Auer小体,但无嗜酸粒细胞和嗜碱粒细胞增多。白血病细胞过氧化物酶反应阳性,按FAB分类诊断为AML(M2)。骨髓和血的
This paper reports a case of ph + acute myeloid leukemia (AML) associated with t (7; 11) recurrence after allogeneic bone marrow transplantation (BMT). Patient, female, 20 years old. Due to persistent fever, cough, anemia, leukocytosis and thrombocytopenia hospitalization. Physical examination: severe anemia, but lymph nodes, liver and spleen are not touched. Hb40g / L, WBC31.3 × 10 ~ 9 / L, naive cells 56%, platelets 0.8 × 10 ~ 9 / L. Myeloid hyperplasia was significantly active, leukemia cells accounted for 69.4%, visible Auer bodies, but no eosinophils and basophils increased. Peroxidase-positive leukemia cells, according to FAB classification diagnosis of AML (M2). Bone marrow and blood