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尿路感染确诊主要依赖尿液细菌培养。而临床上细菌培养的阳性率并不高，其中因素颇多，但细菌Ｌ型形成可能是比较重要因素。该文通过对４４例临床疑似尿路感染患儿进行中段尿细菌Ｌ型培养，其阳性率达３４．１％，在统计学上有高度显著性差异（Ｐ＜０．０１）。细菌Ｌ型由于细胞壁缺陷，使针对细胞壁抗生素类作用明显降低，而作用于干扰细菌蛋白质合成的氨基糖甙类和抑制核酸代谢的大环内酯类抗生素敏感性明显增加，值得临床用药考虑。
Urinary tract infection is diagnosed mainly rely on urine bacterial culture. The positive rate of clinical bacterial culture is not high, many factors, but the formation of bacterial L-type may be more important factor. In this paper, 44 cases of clinically suspected urinary tract infection in children with middle urinary bacterial L-type culture, the positive rate of 34.1%, statistically significant difference (P <0.01). Bacterial L-type cell wall defects due to the role of the cell wall antibiotics significantly reduced, while interfering with bacterial protein synthesis of aminoglycosides and inhibition of nucleic acid metabolism macrolide antibiotics significantly increased sensitivity, worthy of consideration for clinical use.