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在许多组织中,包括膀胱上皮细胞表面,存在血型A、B、O(H)抗原。这些抗原从肿瘤细胞表面的丧失显示与以后肿瘤发生浸润有关,而特定红细胞吸附试验能证实这些抗原的存在或缺乏。我们检查膀胱肿瘤病人和正常对照组的膀胱灌洗液标本,然后膀胱肿瘤病人的结果和原始的活检标本比较细胞表面抗原的存在或缺乏。研究表明此方法简单、可靠,对于筛选和随访膀胱癌病人及预后有重要价值。材料和方法: 12例病人没有膀胱肿瘤史(正常对照组),20例有各期和各级的膀胱移行细胞癌的病人。用F16 Foley氏导尿管常规导尿,用大约50毫升盐水注入空虚的膀胱,再抽出,反复几次。然后膀胱灌洗标本立即分别放到两个瓶子里,一瓶含有70％的酒精,而另一瓶含有10％福尔马林溶液,以固定标本。前者是用
In many tissues, including the surface of bladder epithelial cells, there are blood group A, B, O (H) antigens. The loss of these antigens from the surface of the tumor cells is associated with subsequent tumorigenesis, whereas specific erythrocyte adsorption tests confirm the presence or absence of these antigens. We examined bladder lavage fluid specimens from patients with bladder cancer and normal controls and then compared the results of bladder tumor patients with the original biopsy specimens for the presence or absence of cell surface antigens. Studies have shown that this method is simple and reliable, and has important value for screening and follow-up of patients with bladder cancer and prognosis. MATERIALS AND METHODS: Twelve patients had no history of bladder cancer (normal control group) and 20 patients had transitional cell carcinoma of the bladder at various stages and stages. With F16 Foley ’s catheter conventional catheterization, with about 50 ml of saline into the empty bladder, and then pulled out, repeated several times. The bladder lavage specimens were then immediately placed in two separate bottles, one containing 70% alcohol and the other containing 10% formalin to fix the specimen. The former is used