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呼吸困难是充血性心力衰竭的主要特征,30年前就有人发现增加吸入氧浓度可减少剧烈运动时的通气变化。对急性左心衰患者,为减轻呼吸困难而常规给予氧气吸入,但吸氧对慢性心衰患者运动能力的影响尚无研究。作者研究稳定性左心衰患者吸入室内空气及不同浓度氧气对运动耐量及运动时血流动力学和通气反应的影响。方法 12例稳定性心衰患者,平均年龄55岁(31～66岁)。11例为扩张型心肌病,1例有缺血性心脏病史已行搭桥术。所有患者均经肺功能检查排除气道阻塞性疾病,无近期吸烟史。7例心功能Ⅱ级;5例Ⅲ级(NYRA)。患者连续三日在相同的时间进行同一程
Dyspnea, a major feature of congestive heart failure, was found 30 years ago to increase the level of inhaled oxygen to reduce ventilatory changes during strenuous exercise. In patients with acute left heart failure, oxygen inhalation is routinely given to alleviate dyspnea, but the effect of oxygen administration on exercise capacity in patients with chronic heart failure has not been studied. The authors investigated the effects of inhaled indoor air and different concentrations of oxygen on exercise tolerance and hemodynamic and ventilatory responses during exercise in patients with stable left heart failure. Methods Twelve patients with stable heart failure, mean age 55 years (31 to 66 years). 11 cases of dilated cardiomyopathy, 1 case of ischemic heart disease has been bypass surgery. All patients were obstructed airway obstruction by pulmonary function tests, no recent history of smoking. 7 cases of cardiac function grade Ⅱ; 5 cases of grade Ⅲ (NYRA). The patient ran the same routine at the same time for three consecutive days