论文部分内容阅读
目的探讨不同方法治疗儿童吉兰 -巴雷综合征 ( GBS)的有效性。方法对符合 GBS诊断的 61例患儿随机分为 3组 ,分别给予免疫球蛋白、新鲜血浆和皮质激素治疗 ,并对疗效进行对比观察。结果发现免疫球蛋白治疗组在控制病情进展方面明显优于新鲜血浆和皮质激素组 ( P <0 .0 5和 P <0 .0 1) ;在呼吸肌麻痹、球麻痹的恢复和肌力提高的时间上亦明显提前于其他两组( P<0 .0 5和 P<0 .0 1)。免疫球蛋白可提高重症 GBS患儿机体的免疫力 ,减少继发感染 ,并缩短疗程。结论免疫球蛋白治疗儿童 GBS是一种安全有效的方法。
Objective To investigate the effectiveness of different methods in treating children with Guillain-Barre syndrome (GBS). Methods Sixty-one children who were diagnosed as GBS were randomly divided into three groups, which were treated with immunoglobulin, fresh plasma and corticosteroids, respectively. The curative effect was compared. The results showed that the immunoglobulin treatment group was significantly better than the fresh plasma and corticosteroid group in controlling the progression of the disease (P <0.05 and P <0.01); in respiration muscle paralysis, recovery of ball paralysis and muscle strength Of the time also significantly ahead of the other two groups (P <0 05 and P <0 01). Immune globulin can improve the immune system in children with severe GBS, reduce secondary infection, and shorten the course of treatment. Conclusion Immunoglobulin is a safe and effective method to treat GBS in children.