论文部分内容阅读
目的 探讨Graves病病人运动及感觉神经电生理改变。方法 对 46例Graves病病人和 3 0例正常对照组检测正中神经和胫后神经感觉神经传导速度 (SCV)、运动末端潜伏期 (ML)、复合肌肉动作电位(CMAP)的波幅及F波潜伏期和出现率。结果 Graves病组神经传导改变 43例 (93 5 % ) ,其中胫后感觉神经波幅降低 3 3例 (71 7% ,P <0 0 0 1) ;正中神经和胫后神经运动传导改变分别 4例 (8 6% )和 8例 (17 3 % ) ,与正常对照组比较差异均无显著意义 (P >0 0 5 ) ;正中神经及胫后神经F波异常分别 17例 (3 6 9% )和 14例(3 0 4% ) ,6例病人同时表现F波和运动神经传导异常。结论 神经电生理检查较自觉症状和体征敏感 ,下肢感觉神经损害最常见 ,运动神经元以近端受损为主
Objective To investigate the changes of motor and sensory nerve electrophysiology in patients with Graves disease. Methods The sensory nerve conduction velocity (SCV), the end of motor latency (ML), the amplitude of compound muscle action potential (CMAP) and the latency of F wave were detected in 46 patients with Graves disease and 30 normal controls Occurrence rate. Results There were 43 cases (93.5%) of nerve conduction changes in Graves’ disease group, 33 cases (71.7%, P <0.01) of sensory nerve tibiae receding sensory nerve amplitude. The changes of motor conduction in median nerve and posterior tibial nerve in 4 cases (8 6%) and 8 cases (17 3%) respectively. There was no significant difference between the two groups (P> 0.05) And 14 cases (34%). All 6 patients showed abnormalities of F wave and motor nerve conduction at the same time. Conclusion Neuroelectrophysiology is more sensitive than the symptoms and signs, and sensory nerve damage is the most common in the lower extremities. The motor neurons are mainly proximally damaged